Publicações Selecionadas

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Redes gênicas no controle do desenvolvimento

Araujo H*, Negreiros E, Bier E (2003). Integrins modulate Sog activity in the Drosophila wing. Development 130: 3851-3864. * corresponding author

Fontenele M, Lim B, Oliveira D, Buffolo M, Perlman DH, Schupbach T, Araujo H. (2013). Calpain A modulates Toll responses by limited Cactus/IkappaB proteolysis. Molecular Biology of the Cell 24(18): 2966-2980.

Berni M, Fontenele M, Tobias-Santos V, Cáceres-Rodrigues A, Mury F, Vionette-do-Amaral R, Masuda H, Sorgine M, da Fonseca R, Araujo H. (2014). Toll signals regulate dorsal-ventral patterning and anterior-posterior placement of the embryo in the hemipteran Rhodnius prolixus. EvoDevo Oct 27: 5-38.

Cardoso M, Fontenele M, Lim B, Bisch PM, Shvartsman SY, Araujo HM. (2017). A novel function for the IκB inhibitor Cactus in promoting Dorsal nuclear localization and activity in the Drosophila embryo. Development. 144(16): 2907-2913.

Negreiros, E.; Herszterg, S. Hwa, K.; Câmara, A. Dias, W.; Carneiro, K.; Bier, E.; Todeschini, A.; Araujo, H. N-linked glycosylation restricts the function of short gastrulation to bind and shuttle BMPs. (2018). Development 145(22): dev.167338.

Barros, C.; Cardoso, M; Bisch; Araujo, H.; Lopes, F. (2021). A reaction-diffusion network model predicts a dual role of Cactus/IkappaB to regulate Dorsal/NFkappaB nuclear translocation in Drosophila. PLOS Computational Biology 17(5) e1009040. * corresponding authors

Berni, M.; Mota, J.; Bressan, D.; Ribeiro, L.; Martins, G.; Pereira, J.; Ramos, I.; Nunes-da-Fonseca, R.; Araujo, H. (2023). A pro-BMP function exerted by Rhodnius prolixus short gastrulation reveals great diversity in the role of BMP modulators during embryonic patterning. Open Biology 13(7): 230023.

Julio, A.; Guedes-Silva, T. C.; Berni, M.; Bisch, P. M.; Araujo, H. (2024). A Rhodnius prolixus catalytically inactive Calpain protease patterns the insect embryonic dorsal-ventral axis. Current Research in Insect Science, 100094.

Computational image analysis from the transverse plane of Drosophila embryos.

Oliveira MT, Anhezini L, Araujo HM, Oliveira MF, Couto-Lima CA. Genet Mol Biol. 2024 Feb 19;47(1):e20230202. doi: 10.1590/1678-4685-GMB-2023-0202. eCollection 2024. PMID: 38446983 Free PMC article.

Computational image analysis from the transverse plane of Drosophila embryos. de Sousa DJ, Cardoso MA, Araujo HMM, Lopes FJP, Travençolo BAN. Biosystems. 2025 Nov 12;259:105656. doi: 10.1016/j.biosystems.2025.105656. Online ahead of print. PMID: 41237848

Calpain Proteases and the Evolving Signaling Network in Insect Embryonic Patterning. Julio A, Araujo H. J Exp Zool B Mol Dev Evol. 2025 Jun 1. doi: 10.1002/jez.b.23307. Online ahead of print. PMID: 40452289 Review.

A Rhodnius prolixus catalytically inactive Calpain protease patterns the insect embryonic dorsal-ventral axis.
Julio A, Guedes-Silva TC, Berni M, Bisch PM, Araujo H. Curr Res Insect Sci. 2024 Aug 17;6:100094. doi: 10.1016/j.cris.2024.100094. eCollection 2024. PMID: 39262636 Free PMC article.

Gene Editing in the Chagas Disease Vector Rhodnius prolixus by Cas9-Mediated ReMOT Control. Lima L, Berni M, Mota J, Bressan D, Julio A, Cavalcante R, Macias V, Li Z, Rasgon JL, Bier E, Araujo H. CRISPR J. 2024 Apr;7(2):88-99. doi: 10.1089/crispr.2023.0076. Epub 2024 Apr 1. PMID: 38564197

Boosting life sciences research in Brazil: building a case for a local Drosophila stock center. Oliveira MT, Anhezini L, Araujo HM, Oliveira MF, Couto-Lima CA. Genet Mol Biol. 2024 Feb 19;47(1):e20230202. doi: 10.1590/1678-4685-GMB-2023-0202. eCollection 2024. PMID: 38446983 Free PMC article.

Estratégias de controle biológico de insetos vetores de doenças

Berni M, Fontenele M, Tobias-Santos V, Cáceres-Rodrigues A, Mury F, Vionette-do-Amaral R, Masuda H, Sorgine M, da Fonseca R, Araujo H. (2014). Toll signals regulate dorsal-ventral patterning and anterior- posterior placement of the embryo in the hemipteran Rhodnius prolixus. EvoDevo Oct 27: 5-38.

Mesquita R, Vionette-Amaral R, Lowenberger C,….Araujo H, ….et al. (2015). Genome of Rhodnius prolixus, an insect vector of Chagas disease, reveals unique adaptations to hematophagy and parasite infection. Proc Natl Acad Sci 112 (48): 14936-41.

Berni, M; Lima, L; Bressan, D; Julio, A; Bonfim, L; Simao, Y; Pane, A; Ramos, I; Oliveira, P; Araujo, H. (2022). Atypical strategies for cuticle pigmentation in the blood-feeding hemipteran Rhodnius prolixus. Genetics 221(2): iyac064.

Berni, M.; Mota, J.; Bressan, D.; Ribeiro, L.; Martins, G.; Pereira, J.; Ramos, I.; Nunes-da-Fonseca, R.; Araujo, H. (2023). A pro-BMP function exerted by Rhodnius prolixus short gastrulation reveals great diversity in the role of BMP modulators during embryonic patterning. Open Biology 13(7): 230023.

Lima, L.; Berni, M.; Mota, J.; Bressan, D; Julio, A.; Cavalcante, R.; LI, Z.; Macias, V.; Rasgon, J.; Bier, E.; Araujo, H. (2024). Gene Editing in the Chagas Disease Vector by Cas9-Mediated ReMOT Control. CRISPR Journal. 7(2): 88-99. (Cover article).

Araújo, Helena. The powers and perils of bug editing. Insect Biochemestry and Molecular Biology. V.177, Fev, 2025.

Araujo, Helena; Fontenele, Marcio Ribeiro; da Fonseca, Rodrigo Nunes; Araujo, H. (2011). Position matters: Variability in the spatial pattern of BMP modulators generates functional diversity. genesis 49(9): 698-718.

De Andrade, Daniel Bressan; Araujo, Helena Marcolla. Evolution of the dorsoventral axis in insects: the changing role of Bone Morphogenetic Proteins. Current Opinion in Insect Science. , v.o, p.o – , 2021.

Araujo, Helena; Julio, Alison; Cardoso, Maira. Translating genetic, biochemical and structural information to the calpain view of development. Mechanisms of Development. , v.154, p.240 – 250, 2018.

Nunes da Fonseca, Rodrigo; Berni, Mateus; Tobias dos Santos, Vitória; Pane, Attilio; Araujo, Helena Marcolla. Rhodnius prolixus: From classical physiology to modern developmental biology. GENESIS. , v.55, p.1 – 11, 2017.

Fonseca, R. N.; Gomes, H.; Araujo, H. Capítulo 2- Aspectos Morfofuncionais da Embriologia dos Artrópodes. In: Tópicos Avançados em Entomologia Molecular. 1, 2012, p. 1-34. Link: (Em breve teremos uma versão mais atual)

Lista completa de publicações

Helena Araujo: http://orcid.org/0000-0003-0371-9523